3种氯代烷基有机磷阻燃剂对摇蚊幼虫的毒性效应

doi:10.11934/j.issn.1673-4831.2018.11.013

Abstract

Abstract:

Three typical chlorinated alkyl organophosphate flame retardants (OFRs-Cl), including triphosphate (1,3-dichloro-2-propyl) ester (TDCPP), triphosphate (2-chloro-propyl) ester (TCPP) and triphosphate (2-chloro-ethyl) ester (TCEP), were emerging pollutants for the environment. In the present study, the acute toxic effects of TDCPP, TCPP and TCEP on the fourth instar larvae of Chieonomua riparius were examined by spiked water method. The results show that 5.0 mg·L^-1 TDCPP and TCEP promoted the emergence of larvae, and the promotion effect of TDCPP was stronger than TCEP. All three types of OFRs-Cl had significant effects on the antioxidant enzymes of the larvae of midges. The activities of SOD and CAT in the larvae were induced positively with the increase of OFRs-Cl concentration, and that of MDA was increased at 5.0 mg·L^-1. The expression of HSC70 gene was significantly up-regulated at 5.0 mg·L^-1 of TDCPP and TCEP, and was significantly down-regulated at 5.0 mg·L^-1 of TCPP. In the presence of TDCPP, TCPP and TCEP induced stress, the expression of CYP4G gene were all down-regulated, while the down-regulation was the most significant under TDCPP stress than TCPP and TCEP. A dose-effect relationship was confirmed between TDCPP and SOD or MDA. Different enzymes and genes showed different sensitivity on three OFRs-Cl, yet detoxifying enzymes and related genes showed no significant correlation. Different indexes could be selected as biomarkers for monitoring the varied toxicity derived from three OFRs-Cl on C. riparius.

Key words: chlorinated alkyl organophosphate flame retardant, Chironomus riparius, toxicity effect

CLC Number:

X592

MA Li-li, GAO Yu-xuan, CHEN Wei-qiu, WU Ling-yao, ZHANG Xian-sheng, YU Da-yang, WANG Guo-xiang. Toxic Effects of Three Chlorinated Alkyl Organophosphorus Flame Retardants on Chironomus riparius Larvae[J]. Journal of Ecology and Rural Environment, 2018, 34(11): 1050-1056.

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Toxic Effects of Three Chlorinated Alkyl Organophosphorus Flame Retardants on Chironomus riparius Larvae

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