In order to evaluate and quantify the pollution levels of heavy metals in tailings wetland, and to understand the biological enrichment characteristics of metals, the Tao'erwan wetland of Kundulun Reservoir was selected as the control site, and the water, sediment and toad Strauchbufo raddei were collected in the two wetlands respectively. The heavy metal contents of these samples were determined by inductively coupled plasma emission spectrometry, including toad's muscle, liver, skin and bone, and their consumption risks were assessed by the target risk factor. The results show that heavy metal contents in water and sediment of tailings wetland exceeded the standards to some extent. Cd, Cu, and Pb contents of toad livers in the two wetlands were significantly higher than that in other tissues. Cd and Pb contents of toad muscle in tailing wetland were higher than the National Standards for Food Safety (GB 2762-2017) and Pollution-Free Food Standard for Freshwater Fish (NY 5053-2005), and the risk factors of liver and bone were 4.22 and 1.15, respectively. This study indicated that in tailings wetland, water pollution was mild, and mainly was Cd, but the sediment pollution was heavy, especially for Zn and Pb. The Cu and Zn contents in tissues of toads was higher, and Cd, Cu, Zn, Pb were easily enriched in the liver. Among them, Cu content in toad liver could be used as a warning indicator of heavy metal pollution in the field of biological safety and ecological protection. Livers and bones of local amphibians Strauchbufo raddei poses some consumption risks, and should be given attention by relevant authorities.