Abstract: The ecosystem services value of land use in industrial parks in Qinzhou city of Guangxi Zhuang Autonomous Region has been analyzed based on the ESV method, shadow engineering project method, and replacement cost method. The multi-objective programming model was constructed to form three basic ecological control line scenarios. The impact of land use change on ecosystem service value was studied and analyzed. The optimal scheme was selected among the scenarios from the perspective of ecosystem service value evaluation. The results show that the ecological service value per unit area of positive effect lands were in the order of mangroves > water bodies > ecological vegetation > public green space. The mangrove area had the greatest impact on the ecological service value of industrial parks. The total value of ecological services in each scenario was scenario 2 > scenario 3 > scenario 1. Scenario 2 was the optimal scenario good for the improvement of ecological services of industrial park with an increasing value of 45.136 7 million CNY by only reducing 0.57% of construction land. Based on this scenario, the basic ecological control line was dividing the industrial park into the first level control area and the second level control area. The value of ecological services of the industrial park under scenario 2 can be guaranteed to the maximum extent with the minimal impact on its development. The study scientifically predicts the ecological benefits, provides the basis for the ecological spatial pattern classification, and provides theoretical references for the ecological control and management of industrial parks.