Abstract: The effects of fluoride pollution on photosynthetic products, free amino acid, organic acid and three enzymes in the leaves of white mulberry were studied. Results indicated that fluoride pollution can change the nutrient quality of white mulberry. Based on the effects of fluoride pollution on physiolgical. biochemical characteristics of leaves, the validity of monitoring atmospheric fluoride damage to plant in combination with fluoride and sucrose content in plants as well as symptom of plant are discussed.