Abstract: A total of 37 samples of feces,water and soil were collected from 10 different types of livestock and poultry breeding farms in Jiangsu Province for determination of population of Fecal coliform and Samonella therein.Meanwhile drug resistance of the Escherichia coli isolated from wastewater and effect of animal excreta on population of antibiotic tolerant bacteria in soil and water were analyzed.Results show that of the 10 livestock and poultry farms studied,9 were found discharging animal feces directly into the soil and water without any pre-treatment,and their discharges significantly exceeded the criterion for population of Fecal coliform,and 19% of the fecal samples was found to have Samonella.The count of Fecal coliform in the soils applied with fresh manure was well above 10⁵ g^-1.All the Escherichia coli isolated from the wastewater showed tolerance to a number of drugs and one isolate was even able to tolerate 10 kinds of antimicrobial.The count of tetracycline or streptomycin resistant bacteria in the soil or water amended with fresh manure was much higher than in common soil or water.

Key words: livestock and poultry breeding farm, pathogenic bacterium, drug resistance, antibiotic tolerant bacterium