Abstract: Fish and clams breeding with digested liquid sludge and thicken manure res- pectively in the aspects of production of fish fry, production and its economic efficiency, utilization rate of energy and nitrogen element and the meat quality of fish fries are compared and studied.The results show that digested liquid sludge is much better than chicken manure in the fish and clams breeding. Based on the regular analysis and determination of the quality of manure,bait and water in the experiment, it is suggested that breeding fish fry with digested liquid sludge is the simpler and better way for increasing fry survival rate, fish quality, and economic efficiency and for lowering investment cost.