长江南京段水源水中氨苄西林的时空分布特征及风险评估

doi:10.19741/j.issn.1673-4831.2020.0475

Abstract

Abstract: In order to evaluate the temporal-spatial characteristics and risk assessment of Ampicillin (AMP) in the water source of Nanjing Section of the Yangtze River, 14 sampling sites of Nanjing section of Yangtze River were sampled in November, December 2019 and January, 2020, respectively, and AMP in water was analyzed by SPE-UPLC-MS/MS. The results show that the total mass concentration of AMP ranged from ND to 42.44 ng·L^-1, the average mass concentration was 19.67 ng·L^-1, and the detection rate was 57.5% after testing the samples collected from 14 sampling sites for three consecutive months. The detection rate of AMP in three months was 7.14%, 100% and 66.67%, respectively. The detection concentration and detection rate of AMP in December and January were generally higher than that in November. Risk quotient method was used to assess the risk of AMP in water bodies. The results show that the ecological risk entropy Q_R of AMP in Nanjing Section of the Yangtze River ranged from 0.40 to 0.57, which was a moderate risk. AMP's health risk entropy Q_RH ranged from 3.2×10^-5 to 5.1×10^-5, which had no risk to human health.

Key words: Nanjing Section of Yangtze River, source water, ampicillin, spatio-temporal characteristics, risk assessment

CLC Number:

X502

GONG Run-qiang, WANG Bo, JI Mu-lan, ZHAO Xin, SU Liang-hu, BU Yuan-qing, CHEN Yu, ZHANG Sheng-hu, QIU Hui. Spatiotemporal Characteristics and Risk Assessment of Ampicillin in Water Source of Nanjing Section of the Yangtze River[J]. Journal of Ecology and Rural Environment, 2021, 37(2): 188-193.

References

[1] KLEIN E Y,VAN BOECKEL T P,MARTINEZ E M,et al.Global Increase and Geographic Convergence in Antibiotic Consumption between 2000 and 2015[J].Proceedings of the National Academy of Sciences of the United States of America,2018,115(15):E3463-E3470.
[2] ZHANG Q Q,YING G G,PAN C G,et al.Comprehensive Evaluation of Antibiotics Emission and Fate in the River Basins of China:Source Analysis,Multimedia Modeling,and Linkage to Bacterial Resistance[J].Environmental Science & Technology,2015,49(11):6772-6782.
[3] MITCHELL S M,ULLMAN J L,TEEL A L,et al.PH and Temperature Effects on the Hydrolysis of Three Β-Lactam Antibiotics:Ampicillin,Cefalotin and Cefoxitin[J].Science of the Total Environment,2014,466/467:547-555.
[4] GARY P,WORMSER J,JOSEPH R,et al. Antibiotic and Chemotherapy:Anti-infective Agents and Their Use in Therapy[J].Clinical Infectious Diseases,2004,38(8):1197.
[5] LIYANAGE G,MANAGE P,et al. Occurrence,Fate and Ecological Risk of Antibiotics in Hospital Effluent Water and Sediments in Sri Lanke[J].International Journal of Agriculture and Environmental Research,2016,2(4):909-935.
[6] SALUKELE F,RUGAI D,KASEVA M.Occurrence and Fate of Antibiotics as Trace Contaminants in Wastewater Collection and Disposal Systems Case Study:University of Dar es Salaam Wastewater Stabilization Ponds,in Tanzania[J].Journal of Environment and Earth Science,2017,7(2):1-11.
[7] 方昊,余军楠,王智峰,等.江苏典型中华绒螯蟹养殖区抗生素污染特征与生态风险评估[J].生态与农村环境学报,2019,35(11):1436-1444.[FANG Hao,YU Jun-nan,WANG Zhi-feng,et al.Contamination Characteristics and Ecological Risk Assessment of Antibiotics in Typical Eriocheir sinensis Aquaculture Environments of Jiangsu Province[J].Journal of Ecology and Rural Environment,2019,35(11):1436-1444.]
[8] 赵翰斌,陈鑫,武广哲,等.畜禽养殖场污水处理系统中诺氟沙星抗性菌的筛选及其抗性基因分析[J].生态与农村环境学报,2020,36(2):250-256.[ZHAO Han-bin,CHEN Xin,WU Guang-zhe,et al.Isolation of Norfloxacin Resistant Bacteria and Analysis of Its Antibiotic Resistance Genes from the Wastewater Treatment System of a Livestock Farm[J].Journal of Ecology and Rural Environment,2020,36(2):250-256.]
[9] 何欣,聂晓静,赵红霞,等.SPE-LC-MS/MS同时测定水中9种β-内酰胺类抗生素[J].环境科学与技术,2018,41(2):128-132.[HE Xin,NIE Xiao-jing,ZHAO Hong-xia,et al.Simultaneous Determination of Nine Β-Lactam Antibiotics by SPE-LC-MS/MS in Water[J].Environmental Science & Technology,2018,41(2):128-132.]
[10] 王瑞杰,裘钱玲琳,李国祥,等.宁波月湖水体中抗生素的分布与生态风险评价[J].湖泊科学,2018,30(6):1616-1624.[WANG Rui-jie,QIU-QIAN Ling-lin,LI Guo-xiang,et al.Distribution Characteristics and Ecological Risk Assessment of Selected Antibiotics in Moon Lake,Ningbo City[J].Journal of Lake Sciences,2018,30(6):1616-1624.]
[11] CHMIEL M J,LENART-BOROИ A.Prevalence of Antibiotic-Resistant Escherichia Coli Strains in Selected Rivers of Lesser Poland[J].International Journal of Environmental Science and Technology,2019,16(1):391-400.
[12] ABIA A L K,UBOMBA-JASWA E,MOMBA M N B.High Prevalence of Multiple-Antibiotic-Resistant (MAR) Escherichia coli in River Bed Sediments of the Apies River,South Africa[J].Environmental Monitoring and Assessment,2015,187(10):1-13.
[13] 程伟华,夏利宁,夏绪进,等.新疆塔城地区不同来源大肠杆菌的耐药性调查[J].中国农业科技导报,2015,17(3):152-158.[CHENG Wei-hua,XIA Li-ning,XIA Xu-jin,et al.Survey of Antibiotic Resistance of E.coli from Different Sources in Tacheng Region in Xingjiang[J].Journal of Agricultural Science and Technology,2015,17(3):152-158.]
[14] 董晨,孔筱筱,周璐,等.江苏省2013-2014年腹泻源性气单胞菌流行状况及耐药特征[J].江苏预防医学,2019,30(3):237-239,251.[DONG Chen,KONG Xiao-xiao,ZHOU Lu,et al.Epidemiological Status and Drug Resistant Characteristics of Aeromonas diarrhoea in Jiangsu Province from 2013 to 2014[J].Jiangsu Journal of Preventive Medicine,2019,30(3):237-239,251.]
[15] 刘雪杰,陈伟伟,傅祎欣,等.2015-2018年福建省食源性疾病沙门氏菌监测情况分析[J].中国人兽共患病学报,2020,36(3):223-228.[LIU Xue-jie,CHEN Wei-wei,FU Yi-xin,et al.Surveillance Situation of Salmonella in Foodborne Diseases in Fujian,China,2015-2018[J].Chinese Journal of Zoonoses,2020,36(3):223-228.]
[16] QIAO M,YING G G,SINGER A C,et al.Review of Antibiotic Resistance in China and Its Environment[J].Environment International,2018,110:160-172.
[17] 陈元刚,毕爱民.长江南京段水环境保护浅谈[J].科技资讯,2015,13(14):111.
[18] 封梦娟,杨正标,张芹,等.高效液相色谱-串联质谱法同时测定表层水体中5类40种抗生素[J].色谱,2019,37(5):525-532.[FENG Meng-juan,YANG Zheng-biao,ZHANG Qin,et al.Simultaneous Determination of Five Types of 40 Antibiotics in Surface Water Using High Performance Liquid Chromatography-tandem Mass Spectrometry[J].Chinese Journal of Chromatography,2019,37(5):525-532.]
[19] VERLICCHI P,AL AUKIDY M,GALLETTI A,et al.Hospital Effluent:Investigation of the Concentrations and Distribution of Pharmaceuticals and Environmental Risk Assessment[J].Science of the Total Environment,2012,430:109-118.
[20] PAPAGEORGIOU M,ZIORIS I,DANIS T,et al.Comprehensive Investigation of a Wide Range of Pharmaceuticals and Personal Care Products in Urban and Hospital Wastewaters in Greece[J].Science of the Total Environment,2019,694:133565.
[21] SHI W,ZHANG F X,ZHANG X W,et al.Identification of Trace Organic Pollutants in Freshwater Sources in Eastern China and Estimation of Their Associated Human Health Risks[J].Ecotoxicology,2011,20(5):1099-1106.
[22] HERNANDO M D,MEZCUA M,FERNÁNDEZ-ALBA A R,et al.Environmental Risk Assessment of Pharmaceutical Residues in Wastewater Effluents,Surface Waters and Sediments[J].Talanta,2006,69(2):334-342.
[23] LIU X,STEELE J C,MENG X Z.Usage,Residue,and Human Health Risk of Antibiotics in Chinese Aquaculture:A Review[J].Environmental Pollution,2017,223:161-169.
[24] 范江平,邓斌,张曦,等.奶与奶制品中兽药残留分析[J].黑龙江畜牧兽医,2009(3):70-71.
[25] 周赛冬,戴钰丰,苏龙鹏,等.湖南省武陵山片区肉类食品中氨苄西林残留情况研究[J].应用预防医学,2019,25(4):295-296,299.
[26] 王金良.氨苄西林结晶工艺的研究[D].石家庄:河北科技大学,2011.
[27] KÜMMERER K,HENNINGER A.Promoting Resistance by the Emission of Antibiotics from Hospitals and Households into Effluent[J].Clinical Microbiology and Infection,2003,9(12):1203-1214.
[28] 张丹丹,郭亚平,任红云,等.福建省敖江下游抗生素抗性基因分布特征[J].环境科学,2018,39(6):2600-2606.[ZHANG Dan-dan,GUO Ya-ping,REN Hong-yun,et al.Characteristics of Antibiotic Resistance Genes in Downstream Areas of the Aojiang River,Fujian Province[J].Environmental Science,2018,39(6):2600-2606.]
[29] 张微,潘灿平.一些农药和兽药的ADI值[J].中国兽药杂志,2005,39(3):39-45.[ZHANG Wei,PAN Can-ping.Acceptable Daily Intakes for Agricultural and Veterinary Chemicals[J].Chinese Journal of Veterinary Drug,2005,39(3):39-45.]
[30] WANG H,WANG N,WANG B,et al.Antibiotics Detected in Urines and Adipogenesis in School Children[J].Environment International,2016,89/90:204-211.

Spatiotemporal Characteristics and Risk Assessment of Ampicillin in Water Source of Nanjing Section of the Yangtze River

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	ZHU Kang-wen, CHEN Yu-cheng, YANG Zhi-min, HUANG Lei, ZHANG Sheng, LEI Bo. Research Trends of Agricultural Non-Point Source Pollution Risk Assessment Based on Bibliometric Method [J]. Journal of Ecology and Rural Environment, 2020, 36(4): 425-432.
[2]	MA Shu-xin, QIAO Yong-min, TANG Meng-yao, YANG Hong-yun. Heavy Metal Pollution and Potential Ecological Risk Assessment in Surface Sediments From Lakes Located in Guangzhou City [J]. Journal of Ecology and Rural Environment, 2019, 35(5): 600-607.
[3]	TAN Li-chao, CHENG Yan, ZHU Yu-xuan, BU Yuan-qing. Acute Toxicity and Risk Assessment of Nine Insecticides to Honeybees in Oilseed Rape Fields [J]. Journal of Ecology and Rural Environment, 2019, 35(4): 500-505.
[4]	FANG Hao, YU Jun-nan, WANG Zhi-feng, DING Cheng-cheng, XIA Wei, ZHAO Cheng, YUAN He-zhong, WANG Zhuang, WANG Se, CUI Yi-bin. Contamination Characteristics and Ecological Risk Assessment of Antibiotics in Typical Eriocheir sinensis Aquaculture Environments of Jiangsu Province [J]. Journal of Ecology and Rural Environment, 2019, 35(11): 1436-1444.
[5]	DING Bao-gen, YANG Shu-wang, ZHAO Yu. Study on Spatial-Temporal Characteristics and Driving Factors of Carbon Emission From Planting Industry in the Yangtze River Economic Belt [J]. Journal of Ecology and Rural Environment, 2019, 35(10): 1252-1258.
[6]	ZHAO Han, ZHAO Jun, XU Xiao-ye, WU Shao-hua, ZHU Qing. Spatial Distribution, Sources and Risk Assessment of Polycyclic Aromatic Hydrocarbons in a Rapid Urbanization City: Shenzhen [J]. Journal of Ecology and Rural Environment, 2019, 35(1): 38-45.
[7]	YI Zhao-qin, WANG Hong-feng, MU Li-qiang. Hazard Risk Assessment of Alien Plants in Roadside Ecosystem in Maoershan National Forest Park [J]. Journal of Ecology and Rural Environment, 2018, 34(3): 216-223.
[8]	CHEN Yao, GAN Chun-juan, ZHANG Cai, YUAN Shao-chun, ZHU Zi-qi. Overview on Ecological Risk Assessment Methodologies of Urban Stormwater Ponds [J]. Journal of Ecology and Rural Environment, 2018, 34(12): 1064-1073.
[9]	CHENG Qi-qi, GUO Jin, CHAI Chao, GE Wei. Accumulation Characteristics and Health Risk Assessment of Polycyclic Aromatic Hydrocarbons in Spinach Grown in Diesel Contaminated Soil [J]. Journal of Ecology and Rural Environment, 2018, 34(12): 1145-1152.
[10]	WU Wen-hui, ZOU Hui, ZHU Gang-hui, LIAO Yue-hua, PAN Hai-ting, XIAO Chen-chang, FAN Juan, LI Lu. Heavy Metal Pollution Characteristics and Health Risk Assessment of Groundwater of a Mine Area in Central Hunan [J]. Journal of Ecology and Rural Environment, 2018, 34(11): 1027-1033.
[11]	GAO Dan, TONG Zhi, ZHANG Sheng-hu, JI Gui-xiang, WU Sheng-min, SHI Li-li. Toxicity of Four Typical Organic Phosphorus Flame Retardants to Zebrafish Embryo and Risk Assessment. [J]. Journal of Ecology and Rural Environment, 2017, 33(9): 836-844.
[12]	CHEN Sheng-ke, WAN Yu, YANG Ming-jiao, GAN Xiu-hai. Environmental Health Risk Assessment of Drinking Water Resource of a Village in Guiyang [J]. Journal of Ecology and Rural Environment, 2017, 33(5): 403-408.
[13]	LIAO Jian-hua, ZHOU Jun-ying, CHENG Yan, CHEN Yang. Progress on Development of Upland Crop-Surface Water Exposure Scenarios for Pesticide Risk Assessment [J]. Journal of Ecology and Rural Environment, 2017, 33(4): 289-296.
[14]	LIU Shi-liang, HOU Xiao-yun, ZHANG Yue-qiu, YIN Yi-jie, WANG Jun. Assessment of and Controlling Strategies for Ecological Risks of Land Consolidation Based on Ecosystem Services [J]. Journal of Ecology and Rural Environment, 2017, 33(3): 193-200.
[15]	FENG Yan-hong, Zheng Li-ping, YING Rong-rong, ZHANG Ya, LIN Yu-suo, WANG Guo-qing. Forms of Heavy Metals in Soils of Zinc Mining Area in Northwestern Guizhou Province and Their Environmental Risks [J]. Journal of Ecology and Rural Environment, 2017, 33(2): 142-149.