Abstract: Veterinary medicine and feed additives are now extensively used in animal husbandry and aquaculture,which has become an important factor polluting the eco-environment adn affecting human health.Developed countries have already begun to adopt ecological riks assessment technologies in their management of veterinary drugs,whereas China is just in its starting point.Olaquindox is one of the most commonly used drugs in China.In this study,EU's classic methods and models for ecological risk assessment of veterinary drugs were used to conduct ecological risk assessment of olaquindox.Results show that the predicted environmenttal concentration of olaquindox was 0.313-2.68 mg·kg^-1,0.928-10.2 mg·kg^-1 and 0.281-3.10 mg·kg^-1,in soil,surface water and ground water,respectively,its predicted non-effective concentration was >200 mg·kg^-1,0.5 mg·kg^-1 and 0.5 mg·kg^-1 and 0.5 mg·kg^-1,respectively and its predicited ecological risk <1.34×10^-2,1.856-20.4 and 0.562-6.20,respectively.It is clear that attention should be paid to lowering its aquatic ecological risk in the risk management of olaquindox.It is,therefore,concluded that the ecological risk assessment technology can be used to provide environmental administration of veterinary medicines with effective technical support.

Key words: veterinary medicine, ecological risk assessment, exposure assessment, effect assessment, risk characterization, olaquindox